safetyriskБезопасность и риск фармакотерапииSafety and Risk of Pharmacotherapy2312-78212619-1164Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’)safetyrisk-306Research ArticleОБЗОРЫ И ОРИГИНАЛЬНЫЕ СТАТЬИREVIEWS AND ORIGINAL ARTICLESДоза определяет ядDosis facit venenumАляутдинР. Н.Alyautdin R.NR. N.РомановБ. К.RomanovB. K.Федеральное государственное бюджетное учреждение «Научный центр экспертизы средств медицинского применения» Министерства здравоохранения Российской ФедерацииРоссияScientific Centre for Expert Evaluation of Medicinal Products Russian FederationRussian Federation20140106202203510Copyright © Аляутдин Р.Н., Романов Б.К., 20222022Аляутдин Р.Н., Романов Б.К.Alyautdin R.N R.N., Romanov B.K.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.risksafety.ru/jour/article/view/306

В статье представлена история изучения стрельных ядов,применявшихся в Азии, Африке и Южной Америке. Активные ингредиенты этих ядов активно использовались и продолжают использоваться в традиционной и официальной медицине. Методологический путь создания лекарственных веществ на основе стрельных ядов во многом определил тенденции становления современной фармакологии.

The article presents the history of the exploration of arrow poisons, used in Asia, Africa and South America. The active ingredients of these poisonswere widely used and continue to apply currently in traditional and official medicine. Methodology for development of new drugs based on arrow poisons has determined tendencies of drug design in modern pharmacology. 

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The authors declare that there are no conflicts of interest present.