ОБЗОР СЛУЧАЕВ РАЗВИТИЯ ОСТРОЙ ПЕЧЕНОЧНОЙ НЕДОСТАТОЧНОСТИ ВСЛЕДСТВИЕ ПРИЕМА БИОЛОГИЧЕСКИ АКТИВНЫХ ДОБАВОК

Во всем мире распространено применение биологически активных добавок, которые общедоступны и могут быть приобретены без консультации с лечащим врачом. Считается, что более 50 % взрослого населения во всем мире используют биологически активные добавки. В статье рассмотрены вопросы регламентации рынка биологически активных добавок во всем мире, в том числе Российской Федерации, безопасность применения, развитие нежелательных реакций. Проведен поиск информации по базам данных о развитии лекарственных повреждений печени, связанных с применением биологически активных добавок, содержащих экстракт зеленого чая, усниновую кислоту, 1,3-диметиламиламин, витамин А, анаболические андрогенные стероиды, линолевую кислоту, эфедру, гарцинию камбоджу, используемых для снижения веса. При применении анаболических стероидов выявлен повышенный риск развития нежелательных реакций со стороны печени, сердечно-сосудистой и эндокринной систем. Применение БАД, содержащих экстракт зеленого чая, может привести к тяжелому поражению печени. Анализ нежелательных реакций после применения БАД под торговым названием Гербалайф выявил случаи фальсификации препаратов. Применение препаратов, содержащих витамин А в высоких дозах, эфедру, гарцинию камбоджу приводило к повышению печеночных трансаминаз, психических расстройств, остеопорозу, анорексии.

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