Цифровое сопровождение фармакотерапии для соблюдения режима приема лекарственных препаратов

Актуальность. Соблюдение режима приема лекарственных препаратов (ЛП) является одним из важных условий эффективного и безопасного лечения. Контроль выполнения назначений проводят путем оценки врачом динамики состояния пациента, путем подсчета принятых таблеток и другими косвенными методами. Для увеличения приверженности пациентов к соблюдению режима приема ЛП возможно использование цифровых технологий.

Цель. Провести обзор данных литературы о влиянии режима приема лекарственных препаратов на их эффективность и о цифровых решениях для сопровождения фармакотерапии.

Обсуждение. Низкая приверженность лечению — значимый фактор риска для пациентов. Показано, что наиболее распространенными нарушениями являются пропуск или несвоевременный прием ЛП, а риск ошибок значительно повышается при применении ЛП по индивидуальной схеме по сравнению с классическим вариантом ежедневного приема. Среди значимых последствий нарушения режима приема препарата — обострение заболевания, недостаточная эффективность лечения, развитие нежелательных реакций, лекарственная устойчивость. Перспективными техническими и программными подходами, позволяющими оказать поддержку пациенту для соблюдения режима приема ЛП, являются инновационные технологические решения (таблетницы, флаконы с электронными системами напоминания о времени приема ЛП, цифровые таблетки, интеллектуальные системы контроля приема препаратов), приложения для мобильных телефонов, чат-боты.

Выводы. Показано, что использование цифровых решений для сопровождения фармакотерапии приводит к повышению приверженности пациентов к соблюдению режима приема ЛП и позволяет индивидуализировать схему терапии. Для выбора наиболее перспективных направлений и разработки новых цифровых технологий для контроля фармакотерапии необходимо проведение дальнейших исследований.

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