«Propofol infusion syndrome» - case in a child of 10 years
Abstract
A case description of a serious adverse reaction «propofol infusion syndrome» (PRIS), the existence of which has not been previously described in the literature - neurotoxic effect of deep coma is present. The reaction occurred in a child aged 10 years on the background of prolonged infusion of propofol and excess dose. The data of the literature regarding the etiology and pathogenesis of this syndrome, as well as possible factors responsible for features of the course in the present clinical case are presented.
About the Authors
S. S. Postnikov
N. I. Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
M. N. Kostyleva
N. I. Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
G. P. Bryusov
Russian Pediatric Clinical Hospital
Russian Federation
Russian Federation
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Review
For citations:
Postnikov S.S., Kostyleva M.N., Bryusov G.P. «Propofol infusion syndrome» - case in a child of 10 years. Safety and Risk of Pharmacotherapy. 2016;(4):5-10. (In Russ.)
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