Organic anion transporters and their influence on the toxicity of β-lactam antibiotics
Abstract
This review article describes the classification and mechanism of action of organic anion transporters (OAT). The influence of certain members of this family of transporters on the pharmacokinetics of β-lactam antibiotics.
Keywords
транспортеры,
β-лактамные антибиотики,
SLC,
OAT1,
OAT3,
OAT4,
OATP1A2,
OATP1A2,
OATP1B1,
OATP1B3,
transporters,
β-lactam antibiotics,
SLC,
OAT1,
OAT3,
OAT4,
OATP1A2,
OATP1A2,
OATP1B1,
OATP1B3
About the Authors
V. A. Evteev
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation
Russian Federation
O. V. Muslimova
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation
Russian Federation
I. A. Mazerkina
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation
Russian Federation
N. D. Bunyatyan
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation
Russian Federation
E. V. Shikh
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation
Russian Federation
R. E. Kazakov
Scientific Centre for Expert Evaluation of Medicinal Products
Russian Federation
Russian Federation
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Review
For citations:
Evteev V.A., Muslimova O.V., Mazerkina I.A., Bunyatyan N.D., Shikh E.V., Kazakov R.E. Organic anion transporters and their influence on the toxicity of β-lactam antibiotics. Safety and Risk of Pharmacotherapy. 2017;5(2):70-75. (In Russ.)
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