Физостигмин как антиноцицептивное средство: возможный путь повышения безопасности анестезиологического пособия
Резюме
Создание новых безопасных анальгетических средств является актуальной задачей, решение которой позволит повысить эффективность анестезиологического пособия. Целью настоящего исследования явилось изучение анальгетического действия физостигмина, вводимого интратекально. Антиноцицептивное действие оценивалось с помощью метода «плантарной» стимуляции. Физостигмин при этом пути введения проявлял анальгетическое действие в раннем послеоперационном периоде. Действие физостигмина может быть обусловлено влиянием на спинальные звенья системы контроля афферентного входа.
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Рецензия
Для цитирования:
Немировский А. Физостигмин как антиноцицептивное средство: возможный путь повышения безопасности анестезиологического пособия. Безопасность и риск фармакотерапии. 2016;(3):22-27.
For citation:
Nemirovsky A. Physostigmine as an antinociceptive agent: a possible way to improve the safety of anesthesia. Safety and Risk of Pharmacotherapy. 2016;(3):22-27. (In Russ.)
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